Streetwise portrays the lives of nine desperate teenagers. Thrown too young into a seedy, grown-up world, these runaways and castaways survive, but just barely. Rat, the dumpster diver; Tiny, the teenage prostitute; Shellie, the baby-faced one; and DeWayne, the hustler, are all old beyond their years. All are underage survivors fighting for life and love on the streets of downtown Seattle, Washington